$57.58

ANAGRELIDE

Dosing

The dose of anagrelide will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of anagrelide. If your dose is different, do not change it unless your doctor tells you to do so.

The number of capsules that you take depends on the strength of the medicine.

• For oral dosage form (capsules):
  • For too many platelets in the blood:
    • Adults 0.5 milligrams (mg) four times a day, or 1 mg two times a day, for at least one week. After that, the dose is adjusted to the dose that keeps the number of platelets normal.
    • Children Use and dose must be determined by your doctor.

Storage

To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For anagrelide, the following should be considered:

Allergies Tell your doctor if you have ever had any unusual or allergic reaction to anagrelide. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy Anagrelide has not been studied in pregnant women. This medicine has been found to cause toxic or harmful effects in animals, but was not found to cause birth defects.

It is best to use some kind of birth control while you are taking anagrelide. Tell your doctor right away if you think you have become pregnant while taking anagrelide.

Breast-feeding It is not known whether anagrelide passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.

Children Studies on this medicine have been done only on adult patients, and there is no specific information comparing use of anagrelide in children with use in other age groups.

• Heart disease (known or suspected) Anagrelide can cause unwanted effects on the heart
• Kidney disease Anagrelide rarely causes unwanted effects on the kidney
• Liver disease Blood levels of anagrelide may be increased, possibly increasing the chance of side effects. Also, this medicine sometimes causes unwanted effects on the liver